SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91393e36641525505c17f55136179214459711de51879a32066d2aeae56611fc' 
  AND token = '1a1mCu9NhEldMIX90xWIk+6TQVBD8/4jDJnjFy9A7EI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}