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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '153c79c475f9c7adfaa75fc09b0f0a833056b06a5de314dc37fc746be31fd20e' 
  AND token = 'xVAHOwF58u6CbFiVuf/Lf/fOnqjDmKxSKeBlHM7eJx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}