SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '468accb430f0ae27830fc88e75b255c9f08e4d43edbbc88c96e8f2243726cb01' 
  AND token = 'qa+MDp+216xY6QAc6RAx0fHz4PP+PFHRGGcEVJejlIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}