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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0734b813d81436089087f8194dbdb33db154e430400b00c6bdc9a27664f1109f' 
  AND token = 'A1jMgfm2aQ5iY1mVb+i3WCWNcncVyyiUpmluvaqNqFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}