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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51a80b41ea120e637b8687b516802dd4b716b383254e81e309b4ef7c3e35607f' 
  AND token = 'ZAS0iTiSSfojpM9XG+OgtaaK8Y6ErLFrrCEwfvik2LQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}