SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76070288447974bac95a812cbbc96fa350b1c9de52e666d0f82f7bef1fff8d7b' 
  AND token = 'Wh+OS58Yn39h6o5TKWE2Wdjg+mFeh//p0csVMzbuyWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}