SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b2db77e5e3f68f3554111af8f5a6780faf088ffe7d29ce25984e14458259f80' 
  AND token = 'qmDXQ3FmhKE7kPyGRn5x1irKKSyiWHjmtqonjyVjIdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}