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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b864933360b077a16bb7787c6080c8d0c22570ce3870238c0662fa17d42f125' 
  AND token = 'sXV8Ek3x0q0+UABfFZ4BCY9VP4Q0JfYbY4eG3vSOAAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}