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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c66e653ce0d48531c71ca4e52098cd9c066600670d5e0fd3f55df9acde1f4c1' 
  AND token = 'aQY9NU25HUK10gJx3KMYQAstw6V1nnoD84npmHUgMKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}