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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4db6700c385332cae30c42f164aa9c524f1b26840ee4b185247db6964ab8073' 
  AND token = 'twCFPp1vJIwXUPtx5t5a9RS6AMnOTLAhAvCi0QvH/Ck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}