SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b3045161dd6aed4de8769f3d16357f0441e1153fa575464e642623838e72a98' 
  AND token = 't/7fdx2azLALeuGHPRM5dV7Dode6kLJS1agmfMXdSzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}