SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '733d71722fe9350ae09a3eed0c1ebd34e790dd106c6577bd62d40aab6bf3d7a3' 
  AND token = 'Wx6DDxFvaLc3UbQ/Isek+LjEraz20Bn4UnmhZaAw24M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}