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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '733285313a6c707dc4a59793cae2f04d7eeeea62bc668efe2acc7d8611e6c0e3' 
  AND token = 'ZmRL7Ug5v5FZop5+0i0pdHxQgPAXXSjlJniTDanmUR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}