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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '846b27b4f1395500724cba34019f914b30acc4fe7c7aaf58311a9f2881714c65' 
  AND token = 'NtiOeHS8Cf+6iKMLCpMdJ99UiYRLTlsYHn1d7UmPiNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}