SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '180922f6976728283e81345f1c989a500f8d2eed459a7d32cb50370d0cc6f01d' 
  AND token = 'ZJ37LuWkBnQo8z68GpwepPAUL6QTWkhhjM4XLcUFY4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}