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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29a56a42b9975ce316daacdbc5f9873f6852985b74df91c6d3640f2e2799b212' 
  AND token = 'txXGfw2RKCDkhofc9/k0QcAxQJNIL2agaSNvNlR6BbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}