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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f381e8a4257111a4474d43d816f65a83c05f5d6f9fb28e6486d754365bca471' 
  AND token = 'A7JLB8OIyrTQJN1EmIOQXvJ24RLaLH9uNxO2leZrzIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}