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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b20fda3146d27132e39268605f37a9db05e2e7a930efe8e0e385df66b488738' 
  AND token = '3aEr8snyvwvKMtsEdhCS4XwD8CD5z2m9mlMV/RhA+as=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}