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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '380daeb369b31cafe5174481faf00bc0378ed187e0e9d16d673de979f828d738' 
  AND token = 'y2jNBIQ+FEKrGXANg+S6UxbZMUSDvWJo9j8s5vBPxLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}