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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0c88a4ea1175cb2fb8f491107332d4a9bb8b7dddff383eff04562b6363384d0' 
  AND token = 'fiHGV+4FrKHp9k4LdLKDJlPmEh0u2NkLB7vUCmtH3oU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}