SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f436acb6c787815a3d8674f5f6036d209c2398393d0e5c20638aa6f3bfc4fd74' 
  AND token = 'n9CFSaHMjj5dTeF1zvyMNL1fCU0u9goxlCZstgX5/YQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}