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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0b7f4b6164b0f822f382909d4391a5f459b3fb2a9560d934b5fc22a1611aaec' 
  AND token = '4QuiYQmG1y+MHRy2GkiTVDqfhTmoxz73vUQCfQF6THc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}