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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d208144b6989ff5c6801509219d6c82e5cb21b6fc613f97741c64689b6bc9a6' 
  AND token = '8B/NSQMCO0SFrKRKe9O6EMsCM6e0TF5+xWWFbPuVyqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}