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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81fd0fcd23179de59e11b953799b002ebcb50a6b4451f2c4a58c25bad812a0cf' 
  AND token = 'vn7P2BEqFMYSGKSLmJly0oF7kD00ExAG3dXT1UOPooo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}