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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2f58e2040daf69b69a194de69923ee3517bb71759dfbfb5d7233191a8f7725c' 
  AND token = 'yEHY1dLqVtH1WLhiTz/COrX+ymE9QmRtVgI3DnzYtFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}