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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f81dfca6c61a29af1c6c98e17c9b1c6791e831b819019bd8fbfad0df630f8dd' 
  AND token = '2jY9gV5CaIJdTzEgNZ8Qw0ZGIgaR7obb70y9AF2Khng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}