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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e9291f77d8cc6234813e47e9b5c193a5af1c2317f4dbf053083784d7e1d2d72' 
  AND token = '3XkLNCFRGzVb6Vahc5LPNNQEQFcFfK3N0ul1pRRlqcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}