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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb9b1d95a20e796db23dd8482951060540933e8db530eb4b36e3a88baba22886' 
  AND token = 'CaB7Re+uKlzhC+EQue9I7Gx3tBU/SfgogGxxkb44CuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}