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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd455f115841895ad1e9949caf98ecd6bdff3f5a3027d039d44fd7273731d0251' 
  AND token = 'l+oay39p8zyNwaEDJlqLpgNDy3EZoHOrpNVqm1Bxcu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}