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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72d5a0c1b68637be6255a67e29dc326160e41eada197f8485c7c546f7090b8e1' 
  AND token = '3q8SI06ZR+bnEVUwqa3aLmFpnBUciBdxlNQy1D8ySho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}