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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14487e9cfe2327441f1db300ba4684ab82961d36330cf85fbe4579c0f1e41da2' 
  AND token = 'S7VIby5kjHJCEwrVySs35LG1Cz+dMrza4ujTDUgnfsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}