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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '621a67257a71c2828f1561e437ea03001d6a8b70ae38c4d266a4e7c60004ca6a' 
  AND token = 'QbRljD64W22cG5nHYQm88iD+eCY6zGGH9LBtYAnXV9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}