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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a03b4e8d4a9aaa5402005d762f8d6859700acb5b9e97c125bae3e8fccbe26d7' 
  AND token = 'YMNMp9qeuW/Ls0tHTNdmwbXsuENO43e0gHnlg1AeUpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}