SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e01540dcfa4f5be3ea79aee39fc754c0a57458d23b5e07aa103bde7c49481cd4' 
  AND token = '9xJ86AYemgX650FY1XBCMHmLZyrKMMz8TPCV4oZd9s4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}