SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e32adc248c24d172d948730ae3b3fab11e7fb90d6de2a610507167aee593280' 
  AND token = '+4i218wohXB2rhNjtfwReyzR4T7IpxaH1WdIy7nQARc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}