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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59d7fe09eb552a851e3b35427b97867617c5e3c86f91bc9d720c02b0527d5a65' 
  AND token = 'FjsISQXSKWs5lirgLhNBpkxdroSPjdcTGPUqwpfmv58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}