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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a5e387547c3d88d8ed28896f5079a75280314dcd82991e37d2caaa692403c02' 
  AND token = '2wa/Sa57E+1lKB07lCikc4BIRuMsZO2zHSU47W0GgKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}