SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fd549d66088b64316974f7a032dfe37b75603f033f5d90cb04b055fa74137c3' 
  AND token = 'i0ezqOhXxZVkR4babzy6QqSBVdD+XAH3reUuEvPPkiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}