SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '365e0d33735178b3ace8fe1329aa4e90e37bd5601a93579491fe7622fe437a40' 
  AND token = 'Mk9W77+8NoWClS92AToG2PZXDwQK2lZv2Yk957NrHIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}