SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cdbe4c0b03d1363d0d8571ccf4cd52a7a83afafebd429c41567edd186f27f32' 
  AND token = 'Z9wZEPbzYaCgiDRN9UCxWvdz3PNOV1OMavNjmsWL8SQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}