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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11e0afd9ac5b83f0ed7010e171015df0e1d3e67f169929f2f7516723391ae00b' 
  AND token = 'k377ovlP6KOzG3IMhg9WWIIjrTv8+NYJqyW2cUjcSx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}