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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b5832db35a225136c228ae4c378fe254b282642a3a86d8de4994c1864f30f08' 
  AND token = 'oyxFOyGhvwkK2GJxaD4UWvpS5txyyfHjbCsLAT6hhd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}