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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4922c7b89e864d3a6eeaa4e9e48250f3394f336cb6c747c85240e945b64902e6' 
  AND token = 'RLs0VzkRRle0akWkKmzvZi8ya5KMkwzsfSis1H92QZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}