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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67b61c1d31da9c85ec290c747815f07335d28433700eda9522ab65a17f96fcd1' 
  AND token = '1UZVw27FqRThqnZh0RWi4k818cxPuPeu1Id9ObbRgEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}