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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22a428b52365bcd543aa2c599ba83a5d715971c5aad0341de1eeb73bc353d082' 
  AND token = 'wIVCHBx3385+qblgasNi5trlQXxjZ+jqPGeBwU677qU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}