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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '204b59287b4e403a6df12eb2395559202189472c49eb73eef4d1e876f9a6b322' 
  AND token = 'GQw8q44H8EmKR/OlLR7BEkHdwRGAA6u8WeejtrFSLj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}