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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bab074b8688db8c534780ce8a3de226bdfbd65eaeae38a0a291d8304eb0d0148' 
  AND token = 'TzCziWJMs2OQmjb9XRBsDAVuehsvU1rgEOB5NrBmKOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}