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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad0dca9983661194b4d8d7115e39ce07255ca5dcc3b2f878de9dbb7edc6d663d' 
  AND token = 'zi+CCNs0kpSWoZMsG7YGg/iqWnSf2rvTYFXy9r2EMho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}