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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53531ef6f7e57e3c8653f33d07a76f520d55b77312d5d68f102407fda132ad7c' 
  AND token = 'fW6r7Z0xe+ojUMnN6CjgPfpGY9Ht+gif2kCPZrQxgyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}