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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '215fea402f48b3a05aaac32f7ba8ca002309c85d8a01072d8029bbfb09d2b847' 
  AND token = '7igq4QH1pnGAU6lGaJdECjE+cwz0IsDhnc3Oce1Om44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}